MolGraph
CompoundsDocumentationComplianceAbout
MolGraph

Research chemical sourcing and molecular building block RFQ workflows.

MolGraph is operated by Tessorix Inc.

support@molgraph.com

Products are intended for laboratory research use only and are not for human or veterinary use.

Compounds

  • Compound catalog
  • CAS Search

Company

  • About
  • Contact

Documentation

  • Quality Documentation
  • SDS Disclaimer

Compliance

  • Compliance

Legal

  • Terms
  • Privacy

Copyright © 2026 MolGraph. All Rights Reserved.

Home/Compounds/CAS 76684-89-4
Formula C15H26N2O5MW 314.38Research-use catalog entryCOA/SDS by request

E-64c

CAS Number: 76684-89-4

Sourcing & RFQ

Submit an RFQ to review pricing, availability, lead time, pack size, purity, COA, and supplier SDS for this catalog entry.

Available options

Available Options

Package
10 mg
Purity
95%
Price
Request review
Availability
Shipping review required
Delivery
Shipping review required
Package
100 mg
Purity
95%
Price
Request review
Availability
Shipping review required
Delivery
Shipping review required
Package
25 mg
Purity
95%
Price
Request review
Availability
Shipping review required
Delivery
Shipping review required
Package
250 mg
Purity
95%
Price
Request review
Availability
Shipping review required
Delivery
Shipping review required
Package
50 mg
Purity
95%
Price
Request review
Availability
Shipping review required
Delivery
Shipping review required

Shipping review is required before pricing or stock can be confirmed publicly. Shipping, duties, and documentation fees are confirmed before order acceptance.

Loading RDKit molecule structure...
InChIKey: SCMSYZJDIQPSDI-SRVKXCTJSA-NC15H26N2O5 | MW 314.38

Chemical Absolute Identifiers

CAS Number

76684-89-4

PubChem CID

123664

Molecular Formula

C15H26N2O5

Molecular Weight

314.38 g/mol

Exact Mass

314.184172

InChIKey

SCMSYZJDIQPSDI-SRVKXCTJSA-N

IUPAC Name

(2S,3S)-3-[[(2S)-4-methyl-1-(3-methylbutylamino)-1-oxopentan-2-yl]carbamoyl]oxirane-2-carboxylic acid

SMILES String

CC(C)CCNC(=O)[C@H](CC(C)C)NC(=O)[C@@H]1[C@H](O1)C(=O)O

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

E-64c (CAS 76684-89-4) is listed in the Advanced Chemicals portfolio, with molecular formula C15H26N2O5 and molecular weight 314. 38 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research building-block and synthetic chemistry workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Heterocyclic Building BlocksSynthetic ChemistryResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Cruzipain (Trypanosoma cruzi) — 4 assays; Papain (Carica papaya) — 3 assays; Protein deacetylase HDAC6 (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Cruzipain

Trypanosoma cruzi · SINGLE PROTEIN · 4 qualifying assays · 3 documents · best pChEMBL 7

Experimental evidence source: ChEMBL

Papain

Carica papaya · SINGLE PROTEIN · 3 qualifying assays · 1 documents · best pChEMBL 5.62

Experimental evidence source: ChEMBL

Protein deacetylase HDAC6

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

For supplier-issued SDS or COA, submit a documentation request.

Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

E-64c

Names & Synonyms

E 64cLoxistatin acidEP 475N-(N-(3-carboxyoxirane-2-carbonyl)leucyl)isoamylamine(2S,3S)-3-(((S)-1-(Isopentylamino)-4-methyl-1-oxopentan-2-yl)carbamoyl)oxirane-2-carboxylic acid
Show all synonyms
L-trans-Epoxysuccinyl-Leu-3-methylbutylamide(2S,3S)-trans-Epoxysuccinyl-L-leucylamido-3-methylbutaneEP 475 (Enzyme inhibitor)Loxistatin Acid (E-64C)Loxistatinacidloxistatin-acid(2S,3S)-3-{[(1S)-3-methyl-1-[(3-methylbutyl)carbamoyl]butyl]carbamoyl}oxirane-2-carboxylic acidOpera_ID_1991E-64c, Calpain Inhibitor(+)-(2S,3S)-3-((S)-3-Methyl-1-(3-methylbutylcarbamoyl)butylcarbamoyl)-2-oxiranecarboxylic acidepoxysuccinyl derivative E64ccid_123664E-64c?s7392
External Identifiers
DSSTOX SUBSTANCE ID: DTXSID201370321CHEMBL ID: CHEMBL418661CHEBI ID: CHEBI:188280WIKIDATA ID: Q76010379
Literature & Patent References
DOI 10.6019/CHEMBL4808148HDAC6 screening dataset using tau-based substrate in an enzymatic assay yields selective inhibitors and activatorsDOI 10.21203/rs.3.rs-23951/v1Identification of inhibitors of SARS-CoV-2 in-vitro cellular toxicity in human (Caco-2) cells using a large scale drug repurposing collectionDOI 10.6019/CHEMBL4495564Identification of inhibitors of SARS-Cov2 M-Pro enzymatic activity using a small molecule repurposing screenDOI 10.6019/CHEMBL4495565Cytopathic SARS-Cov2 screening on VERO-E6 cells in a large repurposing effortDOI 10.1021/acs.jmedchem.9b00294Design of Gallinamide A Analogs as Potent Inhibitors of the Cysteine Proteases Human Cathepsin L and <i>Trypanosoma cruzi</i> Cruzain.PMID 31539239Design of Gallinamide A Analogs as Potent Inhibitors of the Cysteine Proteases Human Cathepsin L and <i>Trypanosoma cruzi</i> Cruzain.DOI 10.1021/np401060jDimeric flavonoids from Arrabidaea brachypoda and assessment of their anti-Trypanosoma cruzi activity.PMID 24871307Dimeric flavonoids from Arrabidaea brachypoda and assessment of their anti-Trypanosoma cruzi activity.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

Show non-linked catalog cues

Non-public related references

AloxistatinCAS 88321-09-9
trans-Epoxysuccinyl-L-leucylamido-(4-guanidino)butaneCAS 66701-25-5
(2R,3R)-3-(ethoxycarbonyl)oxirane-2-carboxylic acidCAS 93061-20-2
CA 074 methyl esterCAS 147859-80-1
1,1-Dimethylethyl N-((1S)-3-methyl-1-(((2R)-2-methyl-2-oxiranyl)carbonyl)butyl)carbamateCAS 247068-82-2

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 88321-09-9AloxistatinCAS 66701-25-5trans-Epoxysuccinyl-L-leucylamido-(4-guanidino)butaneCAS 159182-43-14-[[(Hexylamino)carbonyl]amino]-N-[4-[2-[[(2S)-2-hydroxy-3-(4-hydroxyphenoxy)propyl]amino]ethyl]phenyl]-benzenesulfonamideCAS 265129-71-3GW-7647CAS 528-48-3FisetinCAS 10083-24-6PiceatannolCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylate

RFQ questions for CAS 76684-89-4

What are the key identifiers for E-64c (CAS 76684-89-4)?

E-64c is identified by CAS 76684-89-4, with molecular formula C15H26N2O5, molecular weight 314.38, InChIKey SCMSYZJDIQPSDI-SRVKXCTJSA-N.

Does CAS 76684-89-4 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Cruzipain, Papain, Protein deacetylase HDAC6. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 76684-89-4?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for E-64c?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 76684-89-4 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

Can MolGraph support bulk sourcing or custom synthesis review?

Submit the CAS number, quantity, purity requirement, and destination country for sourcing review.