Chemical Identity
Molecular Formula
C12H15BClF2NO2
Molecular Weight
289.51 g/mol
Exact Mass
289.085243
PubChem CID
129946540
SMILES String
CC1(C)OB(c2cc(Cl)nc(C(F)F)c2)OC1(C)C
Names & Synonyms
External Identifiers
Catalog Overview
2-Chloro-6-(difluoromethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine, with CAS 1321518-08-4, is a halogenated pyridine featuring a difluoromethyl group at the 6-position and a pinacol boronate ester at the 4-position, alongside a chlorine atom at the 2-position. This unique combination of functional groups makes it a valuable intermediate in synthetic chemistry. The pinacol boronate ester allows for various cross-coupling reactions, such as Suzuki-Miyaura coupling, while the chloro and difluoromethyl groups offer opportunities for further derivatization or serve as key structural elements in target molecules. It is...
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- Research chemical sourcing
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Read more catalog context
2-Chloro-6-(difluoromethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine, with CAS 1321518-08-4, is a halogenated pyridine featuring a difluoromethyl group at the 6-position and a pinacol boronate ester at the 4-position, alongside a chlorine atom at the 2-position. This unique combination of functional groups makes it a valuable intermediate in synthetic chemistry. The pinacol boronate ester allows for various cross-coupling reactions, such as Suzuki-Miyaura coupling, while the chloro and difluoromethyl groups offer opportunities for further derivatization or serve as key structural elements in target molecules. It is suitable for use in academic and industrial research settings for the synthesis of novel compounds, including potential pharmaceutical intermediates and agrochemicals.
Physical Data
EstimatedEstimated / predicted physical property values for catalog reference.
Appearance
White to off-white solid
Physical State
Solid
Melting Point
95.0 °C
Boiling Point
280.0 °C
Density
1.45 g/cm³
Water Solubility
Slightly soluble
Flash Point
135.0 °C
Applications / Classifications
Biological Target Reference
No verified biological target assignment. This compound is listed primarily as a research or synthetic intermediate.
Preliminary Safety-Style Reference
PreliminaryPreliminary safety-style information for reference only. Not a supplier SDS.
Handling and Storage
- Handle with appropriate personal protective equipment (PPE) including gloves, eye protection, and a lab coat. Use in a well-ventilated area or fume hood to avoid inhalation. Avoid contact with skin and eyes. In case of contact, rinse immediately with plenty of water. Store in a cool, dry place, away from incompatible materials. Consult the Safety Data Sheet (SDS) for comprehensive safety information before handling.
Related Products / Graph Discovery
Related products, derivatives, keywords, and application cues for catalog discovery.
Related CAS / Similar Products
Similar products (text references)
Recommended application cues
Catalog discovery cues, not supplier-verified claims.
Related HS Code / Compliance
Compliance cues are non-linked reference tags and require shipment review.