Chemical Identity
Molecular Formula
C6H4BClF3NO2
Molecular Weight
225.36 g/mol
Exact Mass
224.997571
PubChem CID
49760478
IUPAC Name
[2-chloro-5-(trifluoromethyl)-4-pyridinyl]boronic acid
SMILES String
OB(O)c1cc(Cl)ncc1C(F)(F)F
Names & Synonyms
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External Identifiers
Catalog Overview
(2-Chloro-5-(trifluoromethyl)pyridin-4-yl)boronic acid, with CAS 1167437-28-6, is a highly functionalized boronic acid. Its structure incorporates a pyridine core bearing a chlorine atom, a trifluoromethyl group, and a boronic acid moiety. This combination of functional groups makes it a valuable reagent in synthetic chemistry. The boronic acid group is highly reactive in various coupling reactions, while the chloro and trifluoromethyl substituents can introduce specific electronic and steric properties to target molecules.
Use Context
- Research chemical sourcing
- Custom synthesis and catalog availability review
- COA, SDS, pricing, and fulfillment workflow
Read more catalog context
(2-Chloro-5-(trifluoromethyl)pyridin-4-yl)boronic acid, with CAS 1167437-28-6, is a highly functionalized boronic acid. Its structure incorporates a pyridine core bearing a chlorine atom, a trifluoromethyl group, and a boronic acid moiety. This combination of functional groups makes it a valuable reagent in synthetic chemistry. The boronic acid group is highly reactive in various coupling reactions, while the chloro and trifluoromethyl substituents can introduce specific electronic and steric properties to target molecules. It is typically employed as a key intermediate in the synthesis of complex organic molecules, including pharmaceuticals and agrochemicals, where the pyridine scaffold and trifluoromethyl group are desired structural motifs. This compound is intended for research use only.
Physical Data
EstimatedEstimated / predicted physical property values for catalog reference.
Appearance
white crystalline solid
Physical State
solid
Melting Point
202.0 °C
Boiling Point
294.0 °C
Density
1.55 g/cm³
Water Solubility
0.234 mol/L
Applications / Classifications
Biological Target Reference
No verified biological target assignment. This compound is listed primarily as a research or synthetic intermediate.
Preliminary Safety-Style Reference
PreliminaryPreliminary safety-style information for reference only. Not a supplier SDS.
Handling and Storage
- Handle with appropriate personal protective equipment, including gloves, eye protection, and a lab coat. Use in a well-ventilated area or under a fume hood to avoid inhalation of dust or vapors. Avoid contact with skin and eyes. In case of contact, rinse immediately with plenty of water. Store in a cool, dry place, away from incompatible materials. Consult the Safety Data Sheet (SDS) for detailed hazard information and safe handling procedures. This product is for research use only.
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