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7-Chloro-5-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)-1H-indole

CAS 2254168-92-6Formula C14H16BClFNO2MW 295.55PubChem 145756103

This is a halogenated indole derivative featuring a pinacolborane group. It serves as a versatile functionalized intermediate for research applications.

Loading RDKit molecule structure...
InChIKey: PRAYKQIIRMYDNH-UHFFFAOYSA-NC14H16BClFNO2 | MW 295.55

Chemical Identity

Molecular Formula

C14H16BClFNO2

Molecular Weight

295.55 g/mol

Exact Mass

295.094665

PubChem CID

145756103

SMILES String

CC1(C)OB(c2c(F)cc(Cl)c3[nH]ccc23)OC1(C)C

Names & Synonyms

F93915F982049
External Identifiers
SCHEMBL20577566MFCD34663243

Catalog Overview

7-Chloro-5-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)-1H-indole is a research-use chemical characterized by its indole core, substituted with chlorine and fluorine atoms, and a 4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl (pinacolborane) group. With a molecular formula of C14H16BClFNO2 and a molecular weight of 295. 55, this compound is designed as a functionalized intermediate. The boronic ester functionality makes it particularly useful in various cross-coupling reactions, such as Suzuki-Miyaura coupling, for the synthesis of complex organic molecules.

Use Context

  • Research chemical sourcing
  • Custom synthesis and catalog availability review
  • COA, SDS, pricing, and fulfillment workflow
Read more catalog context

7-Chloro-5-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)-1H-indole is a research-use chemical characterized by its indole core, substituted with chlorine and fluorine atoms, and a 4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl (pinacolborane) group. With a molecular formula of C14H16BClFNO2 and a molecular weight of 295.55, this compound is designed as a functionalized intermediate. The boronic ester functionality makes it particularly useful in various cross-coupling reactions, such as Suzuki-Miyaura coupling, for the synthesis of complex organic molecules. Its halogen substituents can also be leveraged in further synthetic transformations.

Physical Data

Estimated

Estimated / predicted physical property values for catalog reference.

Appearance

white to off-white powder or crystals

Physical State

solid

Melting Point

120.0 °C

Boiling Point

400.0 °C

Density

1.3 g/cm³

Water Solubility

insoluble

Flash Point

180.0 °C

Applications / Classifications

Research intermediateCustom synthesis building block

Biological Target Reference

No verified biological target assignment. This compound is listed primarily as a research or synthetic intermediate.

Preliminary Safety-Style Reference

Preliminary

Preliminary safety-style information for reference only. Not a supplier SDS.

Handling and Storage
  • Handle 7-Chloro-5-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)-1H-indole with appropriate personal protective equipment, including gloves, eye protection, and a lab coat. Use in a well-ventilated area or under a fume hood to avoid inhalation. Avoid contact with skin and eyes. In case of contact, rinse immediately with plenty of water. Store in a cool, dry place, away from incompatible materials. Refer to the Safety Data Sheet (SDS) for comprehensive safety information before use. This product is for research use only and not for human or animal therapeutic or diagnostic use.

Related Products / Graph Discovery

Related products, derivatives, keywords, and application cues for catalog discovery.

Similar products (text references)

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2710293-36-8CAS 2710293-36-8
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Recommended application cues

Research intermediateCustom synthesis building block

Catalog discovery cues, not supplier-verified claims.

Related HS Code / Compliance

HS Code: 293399GHS Pictograms: GHS07Shipment review: Shipment details require review before fulfillment.

Compliance cues are non-linked reference tags and require shipment review.

Catalog navigation

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.