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Home/Compounds/CAS 211555-04-3
Formula C16H14BrN3O3MW 376.2Research-use catalog entryCOA/SDS by request

Whi-P154

CAS Number: 211555-04-3

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Loading RDKit molecule structure...
InChIKey: CBIAKDAYHRWZCU-UHFFFAOYSA-NC16H14BrN3O3 | MW 376.2

Chemical Absolute Identifiers

CAS Number

211555-04-3

PubChem CID

3795

Molecular Formula

C16H14BrN3O3

Molecular Weight

376.2 g/mol

Exact Mass

375.02185

InChIKey

CBIAKDAYHRWZCU-UHFFFAOYSA-N

IUPAC Name

2-bromo-4-[(6,7-dimethoxyquinazolin-4-yl)amino]phenol

SMILES String

COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)O)Br)OC

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Whi-P154 (CAS 211555-04-3) is listed in the Advanced Chemicals portfolio, with molecular formula C16H14BrN3O3 and molecular weight 376. 20 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research building-block and synthetic chemistry workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Heterocyclic Building BlocksSynthetic ChemistryResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Tyrosine-protein kinase JAK3 (Homo sapiens) — 3 assays; Tyrosine-protein kinase JAK2 (Homo sapiens) — 6 assays; Cyclin-dependent kinase 5/CDK5 activator 1 (Homo sapiens) — 4 assays; Insulin receptor (Homo sapiens) — 4 assays; Insulin-like growth factor 1 receptor (Homo sapiens) — 4 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Tyrosine-protein kinase JAK3

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 2 documents · best pChEMBL 5.75

Experimental evidence source: ChEMBL

Tyrosine-protein kinase JAK2

Homo sapiens · SINGLE PROTEIN · 6 qualifying assays · 3 documents

Experimental evidence source: ChEMBL

Cyclin-dependent kinase 5/CDK5 activator 1

Homo sapiens · PROTEIN COMPLEX · 4 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Insulin receptor

Homo sapiens · SINGLE PROTEIN · 4 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Insulin-like growth factor 1 receptor

Homo sapiens · SINGLE PROTEIN · 4 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Safety & Handling

Handling & Storage

  • Keep container tightly closed and dry.
  • Store in a well-ventilated place.
  • Avoid contact with skin and eyes.

PPE

Respiratory protection if needed

First Aid

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  • Rinse mouth with water.

Stability / Reactivity

  • Reactivity.
  • Carbon monoxide, carbon dioxide, hydrogen bromide, nitrogen oxides.

Disposal

  • Waste product: Dispose of remaining and non-recyclable solutions to a licensed company.
  • Contact a professional institution with a waste disposal license to handle this substance.
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Fire Fighting

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Accidental Release

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  • Sweep and shovel up.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

For supplier-issued SDS or COA, submit a documentation request.

Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Whi-P154

Names & Synonyms

WHI-P 154WHI P154MASTPROMjak3 inhibitor ii2-bromo-4-((6,7-dimethoxyquinazolin-4-yl)amino)phenol
Show all synonyms
2-Bromo-4-[(6,7-dimethoxy-4-quinazolinyl)amino]phenol4-(3'-bromo-4'-hydroxyphenyl)amino-6,7-dimethoxyquinazoline2-bromo-4-(6,7-dimethoxyquinazolin-4-ylamino)phenol2-BROMO-4-((6,7-DIMETHOXY-4-QUINAZOLINYL)AMINO)PHENOLC16H14BrN3O3WHI-P154?s2867SDCCGSBI-0086685.P004W0013PHENOL, 2-BROMO-4-((6,7-DIMETHOXY-4-QUINAZOLINYL)AMINO)-
External Identifiers
EC NUMBER: 809-014-9DSSTOX SUBSTANCE ID: DTXSID60274407CHEMBL ID: CHEMBL473773UNII: PG8BT6T9MBWIKIDATA ID: Q59842480
Literature & Patent References
DOI 10.1186/s13148-021-01037-1Synergistic effects of type I PRMT and PARP inhibitors against non-small cell lung cancer cells.DOI 10.6019/CHEMBL4808148HDAC6 screening dataset using tau-based substrate in an enzymatic assay yields selective inhibitors and activatorsPMID 33691794Synergistic effects of type I PRMT and PARP inhibitors against non-small cell lung cancer cells.DOI 10.1021/acs.jmedchem.9b01895Revisiting Aldehyde Oxidase Mediated Metabolism in Drug-like Molecules: An Improved Computational Model.DOI 10.21203/rs.3.rs-23951/v1Identification of inhibitors of SARS-CoV-2 in-vitro cellular toxicity in human (Caco-2) cells using a large scale drug repurposing collectionDOI 10.6019/CHEMBL4495564Identification of inhibitors of SARS-Cov2 M-Pro enzymatic activity using a small molecule repurposing screenDOI 10.6019/CHEMBL4495565Cytopathic SARS-Cov2 screening on VERO-E6 cells in a large repurposing effortPMID 32191458Revisiting Aldehyde Oxidase Mediated Metabolism in Drug-like Molecules: An Improved Computational Model.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

Whi-p131CAS 202475-60-3
N-(3,4-dimethoxyphenyl)-6,7-dimethoxyquinazolin-4-amineCAS 202475-65-8
PD-153035CAS 153436-54-5
4-(3-Hydroxyanilino)-6,7-DimethoxyquinazolineCAS 211555-08-7
PD-153035 hydrochlorideCAS 183322-45-4

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 146535-11-76,7-Dimethoxy-3-phenylquinoxalineCAS 120685-11-2MidostaurinCAS 189232-42-6BohemineCAS 202475-60-3Whi-p131CAS 202475-65-8N-(3,4-dimethoxyphenyl)-6,7-dimethoxyquinazolin-4-amineCAS 153436-54-5PD-153035CAS 211555-08-74-(3-Hydroxyanilino)-6,7-DimethoxyquinazolineCAS 183322-45-4PD-153035 hydrochlorideCAS 100643-71-8DesloratadineCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamate

RFQ questions for CAS 211555-04-3

What are the key identifiers for Whi-P154 (CAS 211555-04-3)?

Whi-P154 is identified by CAS 211555-04-3, with molecular formula C16H14BrN3O3, molecular weight 376.2, InChIKey CBIAKDAYHRWZCU-UHFFFAOYSA-N.

Does CAS 211555-04-3 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Tyrosine-protein kinase JAK3, Tyrosine-protein kinase JAK2, Cyclin-dependent kinase 5/CDK5 activator 1, Insulin receptor, Insulin-like growth factor 1 receptor. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 211555-04-3?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Whi-P154?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 211555-04-3 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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