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Home/Compounds/CAS 211555-08-7
Formula C16H15N3O3MW 297.31Research-use catalog entryCOA/SDS by request

4-(3-Hydroxyanilino)-6,7-Dimethoxyquinazoline

CAS Number: 211555-08-7

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Purity
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Loading RDKit molecule structure...
InChIKey: BNDYIYYKEIXHNK-UHFFFAOYSA-NC16H15N3O3 | MW 297.31

Chemical Absolute Identifiers

CAS Number

211555-08-7

PubChem CID

5687

Molecular Formula

C16H15N3O3

Molecular Weight

297.31 g/mol

Exact Mass

297.111341

InChIKey

BNDYIYYKEIXHNK-UHFFFAOYSA-N

IUPAC Name

3-[(6,7-dimethoxyquinazolin-4-yl)amino]phenol

SMILES String

COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=CC=C3)O)OC

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

4-(3-Hydroxyanilino)-6,7-Dimethoxyquinazoline (CAS 211555-08-7) is listed in the Advanced Chemicals portfolio, with molecular formula C16H15N3O3 and molecular weight 297. 31 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research building-block and synthetic chemistry workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Heterocyclic Building BlocksSynthetic ChemistryResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Vascular endothelial growth factor receptor 2 (Homo sapiens) — 8 assays; Vascular endothelial growth factor receptor 1 (Homo sapiens) — 3 assays; Tau-tubulin kinase 1 (Homo sapiens) — 4 assays; Cyclin-dependent kinase 2 (Homo sapiens) — 3 assays; Ephrin type-B receptor 2 (Homo sapiens) — 3 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Vascular endothelial growth factor receptor 2

Homo sapiens · SINGLE PROTEIN · 8 qualifying assays · 6 documents · best pChEMBL 7.3

Experimental evidence source: ChEMBL

Vascular endothelial growth factor receptor 1

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 3 documents · best pChEMBL 6.7

Experimental evidence source: ChEMBL

Tau-tubulin kinase 1

Homo sapiens · SINGLE PROTEIN · 4 qualifying assays · 3 documents · best pChEMBL 6.62

Experimental evidence source: ChEMBL

Cyclin-dependent kinase 2

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 2 documents · best pChEMBL 6

Experimental evidence source: ChEMBL

Ephrin type-B receptor 2

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 1 documents · best pChEMBL 5.92

Experimental evidence source: ChEMBL

Safety & Handling

Handling & Storage

  • Keep container tightly closed and dry.
  • Store in a well-ventilated place.

PPE

Respiratory protection if needed

First Aid

  • Do not give anything to an unconscious person.
  • Rinse mouth with water.

Stability / Reactivity

  • Reactivity and reaction conditions.
  • Carbon monoxide, carbon dioxide, nitrogen oxides.

Disposal

  • Waste product: Dispose of remaining and non-recyclable solutions to a licensed company.
  • Contact a professional institution with a waste disposal license to handle this substance.
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Fire Fighting

  • If necessary, wear a self-contained breathing apparatus for firefighting.

Accidental Release

  • Do not generate dust when collecting and disposing.
  • Sweep and shovel up.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

For supplier-issued SDS or COA, submit a documentation request.

Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

4-(3-Hydroxyanilino)-6,7-Dimethoxyquinazoline

Names & Synonyms

4-[3-HYDROXYANILINO]-6,7-DIMETHOXYQUINAZOLINEwhi-p180WHI-P180, Hydrochloride3-((6,7-Dimethoxyquinazolin-4-yl)amino)phenol3-[(6,7-Dimethoxy-4-quinazolinyl)amino]phenol
Show all synonyms
DTQ4btk1di83-(6,7-dimethoxyquinazolin-4-ylamino)phenolAnilinoquinazoline deriv. 5WHI-P180(Janex 3)?s65204-(3'-hydroxyanilino)-6,7-dimethoxyquinazoline
External Identifiers
DSSTOX SUBSTANCE ID: DTXSID50943478CHEMBL ID: CHEMBL127907DRUGBANK ID: DB03365METABOLOMICS WORKBENCH ID: 147889WIKIDATA ID: Q27094307
Experimental Spectrum References
13C NMR Spectra
Literature & Patent References
DOI 10.6019/CHEMBL5303304EUbOPEN Chemogenomics Library - IncuCyteDOI 10.6019/CHEMBL5308504Tm Shift (DSF) assay results for EUbOPEN Chemogenomics LibraryDOI 10.1021/acs.jmedchem.1c01942TDP-43 Modulation by Tau-Tubulin Kinase 1 Inhibitors: A New Avenue for Future Amyotrophic Lateral Sclerosis Therapy.PMID 34978799TDP-43 Modulation by Tau-Tubulin Kinase 1 Inhibitors: A New Avenue for Future Amyotrophic Lateral Sclerosis Therapy.DOI 10.1016/j.bmcl.2021.127788Discovery of novel VEGFR-2 inhibitors embedding 6,7-dimethoxyquinazoline and diarylamide fragments.DOI 10.1021/acs.jmedchem.1c00382Discovery of Potent and Brain-Penetrant Tau Tubulin Kinase 1 (TTBK1) Inhibitors that Lower Tau Phosphorylation In Vivo.PMID 33460739Discovery of novel VEGFR-2 inhibitors embedding 6,7-dimethoxyquinazoline and diarylamide fragments.PMID 33944571Discovery of Potent and Brain-Penetrant Tau Tubulin Kinase 1 (TTBK1) Inhibitors that Lower Tau Phosphorylation In Vivo.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

Whi-p131CAS 202475-60-3
6,7-dimethoxy-N-phenylquinazolin-4-amineCAS 21561-09-1
PD-153035CAS 153436-54-5
PD-153035 hydrochlorideCAS 183322-45-4
N-(3,4-dimethoxyphenyl)-6,7-dimethoxyquinazolin-4-amineCAS 202475-65-8

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 202475-60-3Whi-p131CAS 21561-09-16,7-dimethoxy-N-phenylquinazolin-4-amineCAS 153436-54-5PD-153035CAS 183322-45-4PD-153035 hydrochlorideCAS 202475-65-8N-(3,4-dimethoxyphenyl)-6,7-dimethoxyquinazolin-4-amineCAS 120685-11-2MidostaurinCAS 189232-42-6BohemineCAS 319460-85-0AxitinibCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acid

RFQ questions for CAS 211555-08-7

What are the key identifiers for 4-(3-Hydroxyanilino)-6,7-Dimethoxyquinazoline (CAS 211555-08-7)?

4-(3-Hydroxyanilino)-6,7-Dimethoxyquinazoline is identified by CAS 211555-08-7, with molecular formula C16H15N3O3, molecular weight 297.31, InChIKey BNDYIYYKEIXHNK-UHFFFAOYSA-N.

Does CAS 211555-08-7 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Vascular endothelial growth factor receptor 2, Vascular endothelial growth factor receptor 1, Tau-tubulin kinase 1, Cyclin-dependent kinase 2, Ephrin type-B receptor 2. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 211555-08-7?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for 4-(3-Hydroxyanilino)-6,7-Dimethoxyquinazoline?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 211555-08-7 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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