CAS 2223047-09-2Not a supplier-issued SDS

Preliminary Safety Reference

4-Chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)-6-(trifluoromethyl)pyridine

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Preliminary reference disclaimer

This preliminary safety reference is generated from structured MolGraph catalog fields and public reference-style data. It is not a supplier-issued Safety Data Sheet and should not be used as a substitute for supplier-issued documentation, workplace safety review, transport classification, or regulatory compliance decisions. For supplier SDS or COA, submit a documentation request through MolGraph.

Identity

CAS Number

2223047-09-2

Chemical name

4-Chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)-6-(trifluoromethyl)pyridine

Molecular formula

C12H14BClF3NO2

Molecular weight

307.5 g/mol

InChIKey

BFNDUQLSNAWRIQ-UHFFFAOYSA-N

PubChem CID

72214369

Hazard / GHS Reference

GHS Pictograms

GHS07

Catalog reference cue; confirm supplier documentation before use.

Handling & PPE

Handle in a well-ventilated area or fume hood.
Avoid contact with skin, eyes, and clothing.
Keep container tightly closed in a dry and well-ventilated place.
Store away from incompatible materials.
Protect from moisture.
Wear a laboratory coat.
Use appropriate eye protection such as safety glasses or goggles.
Wear compatible protective gloves.
Ensure adequate ventilation or use respiratory protection if needed.

First Aid / Accidental Release

If inhaled, move to fresh air.
In case of skin contact, wash with soap and water.
In case of eye contact, rinse thoroughly with water.
If swallowed, rinse mouth with water.
Seek medical attention if irritation persists.
Avoid dust formation and breathing vapors or mist.
Ensure adequate ventilation.
Evacuate personnel to safe areas.
Sweep up and shovel into suitable disposal containers.

Firefighting / Stability

Use water spray, alcohol-resistant foam, dry chemical, or carbon dioxide.
Wear self-contained breathing apparatus for firefighting if necessary.
Wear full protective firefighting gear.
Prevent runoff from fire control from entering waterways.
Stable under recommended storage conditions.
Avoid strong oxidizing agents.
Avoid strong acids and strong bases.
May react with moisture.

Physical and Chemical Reference

Appearance

white crystalline solid

Catalog reference value; verify against supplier SDS before use.

Physical State

solid

Catalog reference value; verify against supplier SDS before use.

Melting Point

100.0 °C

Catalog reference value; verify against supplier SDS before use.

Boiling Point

300.0 °C

Catalog reference value; verify against supplier SDS before use.

Density

1.4 g/cm³

Catalog reference value; verify against supplier SDS before use.

Water Solubility

insoluble

Catalog reference value; verify against supplier SDS before use.

Flash Point

205.0 °C

Catalog reference value; verify against supplier SDS before use.

Vapor Pressure

Estimated value, unit not specified

Catalog reference value; verify against supplier SDS before use.

Autoignition Temp

410.0 °C

Catalog reference value; verify against supplier SDS before use.

Transport / Shipment Review

HS6

293339

Preliminary catalog cue; verify before compliance decisions.

HS Code

293339

Source: catalog inference.

GHS Pictograms

GHS07

Preliminary catalog cue; verify before compliance decisions.

Compliance

standard-ruo

Preliminary catalog cue; verify before compliance decisions.

Registration Status

DSL: pending; AICS: pending; ENCS: pending; ICSR: pending; TSCA: pending; IECSC: pending; INSQR: pending; REACH: pending; K-REACH: pending; SEA_Regulatory: pending

Registration values are catalog reference status cues and may require jurisdiction-specific review.

Shipment review

Shipment details require review before fulfillment.

Preliminary catalog cue; verify before compliance decisions.

Transport classification must be confirmed using supplier SDS and shipment documentation before dispatch.

Need supplier documentation?

Request through MolGraph:

Supplier-issued SDS
COA
Purity and pack size confirmation
Availability and lead time review
Shipment documentation review

Catalog-Specific Reference Cues

This compound is a pyridine derivative featuring a chloro group, a trifluoromethyl group, and a pinacol boronate ester. It is primarily used as a versatile building block in organic synthesis, particularly for cross-coupling reactions to form new carbon-carbon bonds.
4-Chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)-6-(trifluoromethyl)pyridine, identified by CAS 2223047-09-2, is a highly functionalized pyridine derivative. It features a chlorine atom, a trifluoromethyl group, and a pinacol boronate ester moiety. This compound serves as a versatile building block in organic synthesis, particularly for the construction of complex molecular architectures through palladium-catalyzed cross-coupling reactions, such as the Suzuki-Miyaura coupling. The trifluoromethyl group can impart distinct electronic and steric properties, while the boronate ester provides a reactive site for C-C bond...
Primarily utilized as a chemical building block in organic synthesis, especially for Suzuki-Miyaura cross-coupling reactions. Suitable for researchers developing novel pharmaceutical intermediates or advanced materials.

Related catalog entries

CAS 1218790-05-62-Chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-6-(trifluoromethyl)pyridine CAS 1355067-84-33-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethyl)pyridine CAS 2068737-11-92-Chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-6-(trifluoromethyl)pyridine CAS 741709-67-12-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-(trifluoromethyl)pyridine CAS 2121515-21-52-Chloro-5-(trifluoromethyl)pyridine-4-boronic acid pinacol ester CAS 1622217-23-52-Chloro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)pyridine CAS 2223048-94-85-Chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethyl)pyridine CAS 2377611-69-12-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)pyridine